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Preoperative Radiosurgery for Brain Metastases Shows Promise

Preoperative Radiosurgery for Brain Metastases Shows Promise

TOPLINE: Patients undergoing stereotactic radiosurgery before resection of brain metastases demonstrated low rates of local recurrence, radionecrosis, and nodular leptomeningeal disease at 12 and 24 months, a new analysis found. METHODOLOGY: For patients undergoing resection for brain metastases, postoperative stereotactic radiosurgery improves local control. However, radiosurgery after surgery comes with disadvantages…Read More
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RA Tied to Higher Risk for Specific Heart Failure Type

RA Tied to Higher Risk for Specific Heart Failure Type

TOPLINE: Patients with rheumatoid arthritis (RA) face a higher risk for heart failure (HF) than those without the condition, with the elevated risk primarily driven by HF with preserved ejection fraction (HFpEF). METHODOLOGY: The researchers conducted a retrospective cohort study using data from the Mass General Brigham Biobank to investigate the risk for overall HF […]
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ESG Alone Offers Lasting Benefits for Obesity Comorbidities

ESG Alone Offers Lasting Benefits for Obesity Comorbidities

TOPLINE: Endoscopic sleeve gastroplasty (ESG) as a standalone treatment is a safe and effective minimally invasive therapy that could help achieve significant long-term weight loss and sustained improvements in obesity-related comorbidities. METHODOLOGY: Researchers conducted a 5-year prospective cohort study to evaluate the long-term effects of ESG as monotherapy on obesity-related comorbidities in 404 adult patients […]
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Major Depression in Older Adults Tied to Risky Driving

Major Depression in Older Adults Tied to Risky Driving

Older adults with major depressive disorder (MDD) exhibit riskier driving behaviors than their nondepressed peers, including hard braking, cornering, and unpredictable driving patterns, new research showed. Data for the study came from commercial vehicle data trackers installed in participants’ vehicles. After about a year of follow-up…Read More
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Osteoporosis Medications Linked to Acute Angle Closure Risk

Osteoporosis Medications Linked to Acute Angle Closure Risk

TOPLINE: The use of bisphosphonates, particularly risedronate, in patients with osteoporosis is linked to a higher risk for acute angle closure but not open-angle glaucoma. METHODOLOGY: Researchers conducted a retrospective cohort study using a nationwide health claims database to assess whether the use of oral or intravenous bisphosphonates increased the risk for acute angle closure […]
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Significantly shorter treatment regimens for tuberculosis in children and adults now recommended

Significantly shorter treatment regimens for tuberculosis in children and adults now recommended

Tuberculosis remains a public health crisis. The World Health Organization’s Global Tuberculosis Report released in November 2024 painted a sobering picture; approximately 8.2 million people were newly diagnosed with TB in 2023, the highest number since the organization began global TB monitoring in 1995. A major challenge in tuberculosis treatment has been the long duration […]
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