TOPLINE: In patients with locally advanced rectal cancer who receive neoadjuvant therapy, radiation dose intensification improves pathologic complete response but leads to a small increase in acute toxicities. METHODOLOGY: Preoperative radiochemotherapy is standard of care for treating locally advanced rectal cancer, but 20%-30% of the patients develop metastatic disease…Read More
One August afternoon in 2023, Angela Martin’s cousin called with alarming news. Martin’s 74-year-old aunt had been mauled by four dogs while out for a walk near her home in rural Purlear, North Carolina. She was bleeding heavily from bites on both legs and her right arm…Read More
TOPLINE: Treatments for childhood and young adult cancer (CYAC), especially total body irradiation and allogeneic hematopoietic stem cell transplantation (HSCT), are associated with an increase in the long-term risk of developing diabetes among survivors. METHODOLOGY: Although CYAC survivors are at higher risk of developing diabetes than the general population…Read More
TOPLINE: A home-based cardiac rehabilitation (CR) program has shown similar improvements in fitness, functional capacity, and quality of life as center-based programs in optimally treated patients with heart failure (HF), with both groups demonstrating comparable exercise adherence. This supports home-based rehab as an effective alternative. METHODOLOGY: Researchers conducted a noninferiority trial from 2019 to 2022 […]
A research team at the Institut de Neurociències of the Universitat Autònoma de Barcelona (INc-UAB) has developed a new protein capable of improving memory and reducing tau protein levels in animal models of Alzheimer’s disease. The new compound—HEBE, generated by fusing three proteins—represents a new approach in the search for new strategies to tackle the […]